A new draft toxicological profile for glyphosate is now available for review and public comment from the Agency for Toxic Substances and Disease Registry. Glyphosate is the active ingredient in a variety of broad-spectrum herbicidal products for residential, commercial, and agricultural uses. According to ATSDR, it is typically manufactured for commercial use as a salt available in soluble liquid and granule formulations.  People can be exposed to glyphosate via dermal contact with consumer products, crops, foliage, or soils that contain residues of glyphosate. Exposure can also occur when people inhale mist or spray during the use of products containing glyphosate. Workers may be exposed to the chemical by inhalation, dermal contact, and ocular contact during the manufacture, transport, use, and disposal of glyphosate. ATSDR states that dermal contact appears to be the major route of exposure to glyphosate for people involved in its application. ATSDR’s draft profile for glyphosate explains that human exposures to the chemical are to herbicides that contain glyphosate and other ingredients, and that human studies have reported possible associations between glyphosate herbicide use and various health outcomes. However, glyphosate formulations vary in specific components and their relative proportions, which ATSDR says precludes “meaningful comparisons of toxic effect levels.” Comments on the draft toxicological profile may be submitted via Regulations.gov until July 8, 2019.